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>제품소개>PolyPlus transfection®
Polyplus-transfectionⓇ SA는 유전자 및 세포 치료, 생물학적 제제 제조 및 생명 과학 연구에서 핵산(Nucleic acid) 전달을 위한 혁신적인 솔루션을 개발 및 판매하는 생명 공학 회사입니다. Polyplus-transfectionⓇ 시약은 전 세계적으로 점점 더 많은 핵산 기반 임상 시험에서 유전자 및 세포 요법, 면역 요법 및 백신 접종에 사용됩니다. 바이오닉스는 Polyplus-transfectionⓇ SA의 Distributor로서, 실험 유형에 따른 기술적 리소스와 컨설팅을 제공합니다.
다양한 핵산(DNA, Oligonucleotide, siRNA, miRNA, mRNA) 및 Protein을 연구자가 원하는 수준의 효율로 전달할 수 있는 제품군
뛰어난 안정성을 기반으로, Concept studies, preclinical studies and clinical trials에 최적화된 제품
HEK293, CHO 세포주에서 재조합 단백질 및 항체 (대량)생산등에 최적화된 제품
Viral vector를 이용한 AAV, Lentivirus, Retrovirus생산에 적합
| Category | Products | Molecules | Cell types | Remark |
|---|---|---|---|---|
| Life Science Research |
jetOPTIMUS® | DNA, shRNA |
Adherent Hard-to-transfect cells Primary, Stem & Cancer cell lines |
Small-scale virus production possible CRISPR Genome editing using DNA |
| jetPRIME® | DNA, siRNA, DNA+siRNA, shRNA | Adherent cell lines |
Small-scale virus production possible Co-delivery of different nucleic acids |
|
| jetMESSENGER® | mRNA |
Hard-to-transfect cells Adherent, suspension, Primary cells |
CRISPR Genome editing using mRNA Stem cell differentiation |
|
| INTERFERin® | siRNA, miRNA, mimic miRNA | Adherent & suspension cells | Specific inhibition of gene expression promoted by siRNA | |
| PULSin | Protein, Antibody, Peptide | Adherent & suspension cells | Delivery of protein and antibody for functional studies | |
| jetPEI® | DNA | Adherent & suspension cells | Automated or manual High Throughput Screening (HTS) |
| Category | Products | Molecules | Cell types | Remark |
|---|---|---|---|---|
| Non-Viral in vivo transfection | in vivo-jetPEI® | DNA, siRNA, miRNA, Oligonucleotide | All organs | Various systemic & local administration routes |
| in vivo-jetPEI®-PC |
Pre-clinical in vivo study Custom pack size |
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| GMP in vivo-jetPEI® |
Human Clinical trials Phase I to commercialization, Gene Therapy Custom pack size |
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| in vivo-jetRNA® | mRNA |
All organs (depending on the injection route) |
Systemic or Local administration, in vivo functional studies (Gene expression, CRISPR genome editing) |
|
| in vivo-jetRNA®+ |
| Category | Products | Molecules | Cell types | Remark |
|---|---|---|---|---|
|
Protein and mAb production |
FectoPRO® | DNA | Suspension CHO, HEK-293 & derivatives |
Enhanced Transient Gene Expression (TGE) in suspension CHO and HEK-293 |
| FectoCHO® Expression System | Suspension CHO cells such as CHO-K1, CHO-S or ExpiCHO™-S |
Novel CHO chemically defined medium as FectoCHO®
CD Expression medium & FectoPRO® Expression Booster included |
| Category | Products | Molecules | Cell types | Remark |
|---|---|---|---|---|
| Virus vector for Gene & Cell Therapy | PEIpro® | DNA, co-delivery of several plasmid DNA |
HEK-293, HEK-293, BHK, VERO cell lines, virus packaging cell lines (adherent or suspension cultures) |
Large-scale virus production : AAV, Lentivirus, influenza virus, retrovirus, VLP |
| PEIpro®-HQ |
Large-scale virus production for Pre-clinical & early phase clinical trial |
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| PEIpro®-GMP |
Large-scale virus production for Clinical trial & commercialization |
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| FectoVIR®-AAV | DNA, co-delivery of several plasmid DNA |
HEK-293, HEK-293 derivatives grown in suspension cultures |
Recombinant Adeno-Associated Viruses (AAV) virus production in suspension cells |
|
| FectoVIR®-AAV GMP |
GMP compliant Recombinant Adeno-Associated
Viruses (AAV) virus production in suspension
cells
|
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